Improve the overall appearance and texture of the skin. Normally, glycolic acid is a little too irritating to be used daily, but Gly Derm has solved that problem. Gly Derm Glycolics help the skin retain more moisture making skin smoother, healthier, and younger-looking. Many Glycolic acid products simply can't do what they promise. And most over-the-counter brands have been neutralized or buffered. If you want the most effective glycolic acid formulations available, rely on the power of physician-strength Gly Derm. The plus line which contains twice the percentage of glycolic acid should only be used by those customers who have used glycolics previously and demonstrated tolerance to these concentrations without irritation.